Crohn’s Disease

Type

Clinical Features

Ulcerative colitis 

• Chronic inflammatory condition with relapsing and remitting episodes of inflammation in colonic mucosal layer
• Involves colon in continuous manner without skip lesions
  • Rectum (proctitis)
  • Rectum and sigmoid colon (proctosigmoiditis)
  • Colon to splenic flexure (left sided colitis)
  • Extension beyond splenic flexure (extensive colitis)

Crohn’s Disease 

• Transmural inflammation of entire GI tract with skip lesions
  • Segments of normal appearing areas interrupted by diseased areas
• Possible findings in GI tract
  • Fibrosis
  • Obstruction
  • Sinus tracts (micro-perforation and fistulas)
• Typical distribution 
  • 80% of patients with small bowel involvement
  • 50% of patients with involvement of ileum and colon
  • 20% of patients with only colonic disease
  • 33% of patients with perianal disease
  • 5-15% have involvement of mouth or gastroduodenal area