Classification of inflammatory bowel disease (IBD) Ulcerative ColitisType Clinical Features Ulcerative colitis Chronic inflammatory condition with relapsing and remitting episodes of inflammation in colonic mucosal layer Involves colon in continuous manner without skip lesions Rectum (proctitis) Rectum and sigmoid colon (proctosigmoiditis) Colon to splenic flexure (left sided colitis) Extension beyond splenic flexure (extensive colitis) Crohn’s Disease Transmural inflammation of entire GI tract with skip lesions Segments of normal appearing areas interrupted by diseased areas Possible findings in GI tract Fibrosis Obstruction Sinus tracts (micro-perforation and fistulas) Typical distribution 80% of patients with small bowel involvement 50% of patients with involvement of ileum and colon 20% of patients with only colonic disease 33% of patients with perianal disease 5-15% have involvement of mouth or gastroduodenal area (Next Lesson) Possible pathogenesis of IBD Back to Ulcerative Colitis No Comments Comments are closed.
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