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Background of IBS | The Art of Clinical Medicine
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Irritable Bowel Syndrome (IBS)

Home Irritable Bowel Syndrome (IBS) Background of IBS

Background of IBS

Irritable Bowel Syndrome (IBS)


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Type Clinical features 
Possible pathogenesis of IBS 
  • Alteration in fecal microflora 
  • Altered colonic motility 
  • Hypersensitivity of visceral Gi receptors in response to stimuli 
  • Intestinal mucosal inflammation in some patients 
  • Psychosocial dysfunction 
Associated conditions 
  • Chronic fatigue syndrome (systemic exertion intolerance disease) 
  • Fibromyalgia 
  • Functional dyspepsia 
  • GERD 
  • Non-cardiac chest pain 
  • Psychiatric conditions 
    • Major depression 
    • Anxiety 
    • Somatization 
(Next Lesson) Clinical presentation of IBS
Back to Irritable Bowel Syndrome (IBS)

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