["Abnormal Liver Function Tests","Acne vulgaris","Acute Bronchitis","Acute Kidney Injury","Adrenal Insufficiency","Allergic Rhinitis","Anemia","Approach to Abdominal Pain","Approach to Acid Base Disorders","Approach to Bone Loss","Approach to Bright Red Blood Per Rectum (BRBPR)","Approach to Cervical cancer screening","Approach to Chest Pain","Approach to Constipation","Approach to Cough","Approach to Dementia","Approach to Diarrhea","Approach to Dizziness","Approach to Dysphagia and Odynophagia","Approach to EKG","Approach to Falls","Approach to Fatigue","Approach to Fever","Approach to Hematuria","Approach to Hemoptysis","Approach to Hypercoagulable Disorders","Approach to Hyperkalemia","Approach to Hypernatremia","Approach to Hyperprolactinemia","Approach to Hypocalcemia","Approach to Hypoglycemia","Approach to Hypokalemia","Approach to Hyponatremia","Approach to Hypothyroidism","Approach to Jaundice","Approach to Low Back Pain","Approach to Muscle weakness","Approach to Nausea and Vomiting","Approach to Neck Pain","Approach to Palpitations","Approach to Peripheral Edema","Approach to Proteinuria","Approach to Seizure","Approach to Shortness of Breath (Dyspnea)","Approach to Splenomegaly","Approach to Syncope","Approach to Thyroid Nodule","Approach to Unintentional Weight Loss","Asthma","Bell\u2019s Palsy","Benign Prostatic Hyperplasia (BPH)","Bleeding Disorders","Breast cancer screening","Bronchiectasis","Celiac disease","Chronic Kidney Disease","Chronic Obstructive Pulmonary Disease (COPD)","Cirrhosis","Colon cancer screening","Congestive Heart Failure (CHF)","Crohn\u2019s Disease","Cushing\u2019s Syndrome","Delirium","Depression","Diabetes Insipidus","Diverticulosis and Diverticulitis","Dyspepsia","Gastroesophageal Reflux Disease (GERD)","Generalized Anxiety Disorder (GAD)","Headache","Hearing loss","Helicobacter pylori (H. pylori)","Hemorrhoids","Hepatitis B","Hepatitis C","Hypercalcemia","Hypertension","Irritable Bowel Syndrome (IBS)","Kidney stones","Leukocytosis","Leukopenia","Lipid Disorders","Lymphadenopathy","Meningitis and Encephalitis","Microscopic Colitis","Obstructive Sleep Apnea","Pancreatitis","Peptic Ulcer Disease (PUD)","Pericardial Disease","Pneumonia","Stroke and TIA","Ulcerative Colitis","Upper Gastrointestinal Bleeding","Urinary Dysfunction","Urinary Tract Infection (UTI)","Vitamin D deficiency"]

Acne vulgaris

Pathogenesis of acne vulgaris

Type	Clinical features
General	Chronic or recurrent development of papules, pustules, or nodules on face, neck, trunk, or proximal upper extremities
Development of lesions	*Microcomedo* *(plural microcomedones)* Small, hyperkeratotic plug of corenocytes in lower portion of follicular infindibulum Precursor for acne lesions *Progression of lesions* Closed comedones (“whiteheads) Open comedones (“blackheads”) Inflammatory papules Pustules Nodules
Factors leading to lesions	Follicular hyperkeratinization Increased sebum production by sebaceous glands possibly due to increased androgens Increased amount of skin flora bacteria Cutibacterium acnes (C. acnes, formerly Propionibacterium acnes) Inflammation
Risk factors for acne development	Repetitive skin trauma High glycemic load diet Psychologic stress Insulin resistance

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